Research Projects
Project #1: Antimicrobial Nanomaterials
To synthesize and characterize nanomaterials for combating antibiotic-resistant bacteria and viruses of public health concern.
Project #2: Bioimaging and Biosensing
To develop a bioimaging and biosensing platform for the in vitro study of the molecular and spatial binding mechanism of antimicrobial nanomaterials.
Project #3: Separation and detection of environmental pollutants
To develop an ecofriendly, physicochemical-based process for the separation of metallic nanoparticles and their ionic species from environmental and biological matrices.
Project #4: Forensic detection
To develop instrumentation-based methods for the detection of illicit drugs and fraudulent consumer products.
Representative Publications
Antibiotics 2023, 12(8), 1208-1264.
2023 Scientific Editors’ Choice
Nanosilver: An Old Antibacterial Agent with Great Promise in the Fight against Antibiotic Resistance
K. G. Kaiser, V. Delattre, V. J. Frost, G. W. Buck, J. V. Phu, T. G. Fernandez, and I. E. Pavel
ACS Omega 2018, 3(1), 514-523.
A LC-MS/MS-Based Method for the Multiplex Detection of 24 Fentanyl Analogs and Metabolites in Whole Blood at Sub ng mL-1 Concentrations
K. E. Strayer, H. M. Antonides, M. P. Juhascik, R. Daniulaityte, and I. E. Pavel
Environmental Science and Technology 2016, 50, 7056-7065.
Freshwater crayfish: a potential benthic-zone indicator of nanosilver and ionic silver pollution
S. W. Brittle, S. L. A. Paluri, D. P. Foose, M. T. Ruis, M. T. Amato, N. H. Lam, B. Buttigieg, Z. E. Gagnon, and I. E. Pavel
The New England Journal of Medicine 2013, 370(1), 88-89.
Mechanism of Drug Failure in Fusarium Keratitis, 2004-2006.
J. D. Bullock, L. B. Elder, R. E. Warwar, S. A. Snyder, and I. E. Pavel
Bone 2013, 53, 421-429.
Evaluating the abnormal ossification in tibiotarsi of developing chick embryos exposed to 1.0 ppm doses of platinum group metals by spectroscopic techniques.
A. C. Stahler, J. L. Monahan, J. M. Dagher, J. D. Baker, M. M. Markopoulos, D. B. Iragena, B. M. NeJame, R. Slaughter, D. Felker, L. W. Burggraf, L. A. C. Isaac, D. Grossie, Z. E. Gagnon, and I. (Sizemore) Pavel
Food and Chemical Toxicology 2022, 166 (113228), 1-11.
Biodistribution and toxicity of antimicrobial ionic silver (Ag+) and silver nanosilver (AgNPs+) species after oral exposure, in Sprague-Dawley rats
J. Ryan, P. Jacob, A. Lee, Z. Gagnon, and I. E. Pavel
Journal of the American Chemical Society 2010, 132, 10970-10972.
Size selection and concentration of silver nanoparticles by tangential flow ultrafiltration for SERS-based biosensors.
J. C. Trefry, J. L. Monahan, K. M. Weaver, A. J. Meyerhoefer, M. M. Markopoulos, Z. S. Arnold, D. P. Wooley, and I. E. Pavel
Environmental Science and Technology 2018, 52, 2854-2862.
A Raman-based Imaging Method for Characterizing the Molecular Adsorption and Spatial Distribution of Silver Nanoparticles to Hydrated Mineral Surfaces
S. W. Brittle, D. P. Foose, K. A. O’Neil, J. M. Sikon, J. K. Johnson, A. C. Stahler, J. Ryan, S. R. Higgins, and I. E. Pavel
Small 2017, 13(23), 1603093 (1-15).
Analytical-Based Methodologies for Examining the In Vitro ADMEs of Silver Nanoparticles
S. L. A. Paluri, J. D. Ryan, N. H. Lam, D. Kanel, and I. E. Pavel